GATE Biotechnology Syllabus 2018 pdf
Get details of Biotechnology Syllabus for GATE Exam 2018. Biotechnology is covered in various engineering branches like Bioinformatics, Biomedical engineering and in biotechnology itself. Pattern of examination for GATE biotechnology is same as that of biomedical and bioinformatics.
You can check out GATE exam pattern for Biotechnology from our website. A table showing GATE paper pattern for Biotechnology is given below. In this article one can check for GATE Biotechnology 2018. You can check out GATE exam pattern for Biotechnology from the table drawn below. So, make your self to prepare well by knowing the GATE Biotechnology Syllabus
Graduate Aptitude Test in Engineering (GATE) is an examination that primarily tests the comprehensive understanding of the candidates in various undergraduate subjects in Engineering/Technology/Architecture and post-graduate level subjects in Science. The GATE score of a candidate reflects a relative performance level in a particular subject in the examination across several years.
GATE Biotechnology Syllabus 2018
Here we are providing the detailed syllabus for GATE Biotechnology for students reference purpose :
|Exam Section||Marks Weightage|
|General Aptitude||15% of total marks|
|Engineering Mathematics||15% of total marks|
|Subject questions||70% of total marks|
About GATE Biotechnology
Biotechnology is the use of living systems and organisms to develop or make products, or “any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use”
General Aptitude – GATE Syllabus 2018
General Aptitude (GA) section is common to all the papers. The General Aptitude section is designed to test your language, analytical and quantitative skills. For full details about General Aptitude Syllabus Click on General Aptitude Syllabus
- Linear Algebra
- Differential Equations
- Probability and Statistics
- Numerical Methods
Matrices and determinants, Systems of linear equations, Eigen values and Eigen vectors.
Limit, continuity and differentiability, Partial derivatives, Maxima and minima, Sequences and series, Test for convergence, Fourier Series.
Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients, Cauchy’s and Euler’s equations, Laplace transforms, PDE- Laplace, heat and wave equations.
Probability and Statistics:
Mean, median, mode and standard deviation, Random variables, Poisson, normal and binomial distributions, Correlation and regression analysis.
Solution of linear and nonlinear algebraic equations, Integration of trapezoidal and Simpson’s rule, Single and multistep methods for differential equations.
SUBJECT QUESTIONS (Biotechnology)
Detailed syllabus for Agricultural Engineering syllabus is given below which carries the weightage of 72% of total marks.
- General Biotechnology
- Recombinant DNA Technology
- Plant and Animal Biotechnology
- Bioprocess Engineering and Process Biotechnology
Biochemistry: Biomolecules – structure and functions; Biological membranes, structure, action potential and transport processes; Enzymes- classification, kinetics and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids) photosynthesis, respiration and electron transport chain; Bioenergetics
Microbiology: Viruses – structure and classification; Microbial classification and diversity(bacterial, algal and fungal); Methods in microbiology; Microbial growth and nutrition; Aerobic and anaerobic respiration; Nitrogen fixation; Microbial diseases and host-pathogen interaction
Cell Biology: Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-Cell communication, Cell signaling and signal transduction
Molecular Biology and Genetics: Molecular structure of genes and chromosomes; Mutations and mutagenesis; Nucleic acid replication, transcription, translation and their regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics (plasmids, transformation, transduction, conjugation); Horizontal gene transfer and Transposable elements; RNA interference; DNA damage and repair; Chromosomal variation; Molecular basis of genetic diseases
Analytical Techniques: Principles of microscopy-light, electron, fluorescent and confocal; Centrifugation- high speed and ultra; Principles of spectroscopy-UV, visible, CD, IR, FTIR, Raman, MS, NMR; Principles of chromatography- ion exchange, gel filtration, hydrophobic interaction, affinity, GC,HPLC, FPLC; Electrophoresis; Microarray
Immunology: History of Immunology; Innate, humoral and cell mediated immunity; Antigen; Antibody structure and function; Molecular basis of antibody diversity; Synthesis of antibody and secretion; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organ; B and T cells and macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation of immune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus host reaction.
Bioinformatics: Major bioinformatic resources and search tools; Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny); Data mining and analytical tools for genomic and proteomic studies; Molecular dynamics and simulations (basic concepts including force fields, protein-protein, protein-nucleic acid, protein-ligand interaction)
Recombinant DNA Technology
Restriction and modification enzymes; Vectors; plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; mammalian and plant expression vectors; cDNA and genomic DNA library; Gene isolation, cloning and expression ; Transposons and gene targeting; DNA labeling; DNA sequencing; Polymerase chain reactions; DNA fingerprinting; Southern and northern blotting; In-situ hybridization; RAPD, RFLP; Site-directed mutagenesis; Gene transfer technologies; Gene therapy
Plant and Animal Biotechnology
Totipotency; Regeneration of plants; Plant growth regulators and elicitors; Tissue culture and Cell suspension culture system: methodology, kinetics of growth and, nutrient optimization; Production of secondary metabolites by plant suspension cultures; Hairy root culture; transgenic plants; Plant products of industrial importance
Animal cell culture; media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macro-carrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals
Bioprocess Engineering and Process Biotechnology
Chemical engineering principles applied to biological system, Principle of reactor design, ideal and non-ideal multiphase bioreactors, mass and heat transfer; Rheology of fermentation fluids, Aeration and agitation; Media formulation and optimization; Kinetics of microbial growth, substrate utilization and product formation; Sterilization of air and media; Batch, fed-batch and continuous processes; Various types of microbial and enzyme reactors; Instrumentation control and optimization; Unit operations in solid-liquid separation and liquid-liquid extraction; Process scale-up, economics and feasibility analysis
Engineering principle of bioprocessing- Upstream production and downstream; Bioprocess design and development from lab to industrial scale; Microbial, animal and plant cell culture platforms; Production of biomass and primary/secondary metabolites; Biofuels, Bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins; Industrial application of chromatographic and membrane based bioseparation methods; Immobilization of biocatalysts (enzymes and cells) for bioconversion processes; Bioremediation-Aerobic and anaerobic processes for stabilization of solid / liquid wastes
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